CIBA Foundation Symposium on Pulmonary Structure and Function

By A. V. S. De Reuck; Maeve O'Connor | Go to book overview
72 hours. Evidence is presented to suggest that in this way the volumes of the lungs are approximately the same as their volumes in life at full inspiration.Examples of emphysema seen in slices impregnated with barium sulphate are illustrated. The amount of emphysema is estimated by draining the slice for two minutes at an angle of 45° so that emphysematous areas collapse and become more noticeable to the naked eye. The slice is traced onto glass, then onto paper which is cut out and weighed, and the amount of emphysema is expressed as the area of emphysema as a percentage of the area of the whole slice.
REFERENCES
BARNHARD H. J., PIERCE J. A., JOYCE J. W., and BATES J. H. ( 1960). Amer. J. Med., 28, 51.
HARTROFT W. S., and MACKLIN C. C. ( 1944). Trans. roy. Soc. Canad., Sect. V, 38, 63.
HEARD B. E. ( 1958). Thorax, 13, 136.
HEARD B. E. ( 1959). Thorax, 14, 58.
HEARD B. E. ( 1960). Amer. Rev. resp. Dis., 82, 792.
LIEBERMEISTER G. ( 1907). Zbl. allg. Path. path. Anat., 18, 644.
MCILROY M. B. ( 1952). Thorax, 7, 285.
MEAD J. ( 1961). Physiol. Rev., 41, 281.

DISCUSSION

Hugh-Jones: When you say "diffuse" emphysema, are you using that term to refer to a different type from the centrilobular one, Dr. Heard? Is it what some people call "panacinar"? Presumably you accept that either of these types can be generalized or localized within the lung? I rather feel that the term "diffuse" could be misinterpreted to apply to its distribution throughout the lung.

Heard: By the term diffuse emphysema I mean that there may be changes in all parts of the secondary lobule, whereas in centrilobular emphysema, as the term indicates, changes are mainly confined to the middle parts of the lobule and the outer parts may be normal. Most of the confusion among non-pathologists about emphysema is due to a

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