Unity and Diversity in Biochemistry: An Introduction to Chemical Biology

By Marcel Florkin; T. Wood | Go to book overview

Contents
Translator's Prefaceix
Introductionxi
PART ONE
CHAPTER I: THE BIOSPHERE1
CHAPTER II: CONSTITUENTS OF THE BIOSPHERE7
I. The three principal biochemical structures8
II. Other chemical structures of general interest30
CHAPTER III: MODES OF LINKAGE BY COVALENT BONDS57
I. "Oside" Linkage57
II. Ester linkage (and anhydride linkage)61
III. Peptide bond77
CHAPTER IV: MACROMOLECULES83
I. Polysaccharides85
II. Proteins93
III. Nucleoproteins107
IV. Metalloproteins111
V. Lipoproteins127
PART TWO--ENZYMES AND BIOCHEMICAL ENERGETICS
CHAPTER I: GENERAL PRINCIPLES OF BIOCHEMISTRY131
I. Free energy131
II. Energy coupling136
III. Energy rich bonds137
IV. The phosphate cycle138
V. Biological oxido-reductions and the generation of energy-rich bonds138
VI. The cellular dynamo145
VII. The pyrophosphate bond and cellular work146
VIII. Chemical equilibrium and the stationary state147
CHAPTER II: ENZYMES151
I. Definition151
II. Enzymes and activators152
III. Classification of enzymes152
IV. Kinetics166
V. The mechanism of action of enzymes and coenzymes171
PART THREE--CHEMICAL REACTIONS IN THE BIOSPHERE
INTRODUCTION179
CHAPTER I: DESTRUCTIVE AND NON-DESTRUCTIVE METHODS IN MODERN BIOCHEMISTRY181
I. From the whole organism to the pure enzyme181
II. Biochemical investigation and the use of isotopes182
III. The use of mutant strains of micro-organisms184

-v-

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Unity and Diversity in Biochemistry: An Introduction to Chemical Biology
Table of contents

Table of contents

  • Title Page iii
  • Contents v
  • List of Abbreviations vii
  • Translator's Preface ix
  • Introduction xi
  • Part One xv
  • Chapter I - The Biosphere 1
  • Chapter II - Constituents of the Biosphere 7
  • References 14
  • References 24
  • References 30
  • References 37
  • References 43
  • References 56
  • Chapter III - Modes of Linkage by Covalent Bonds 57
  • References 60
  • References 62
  • References 77
  • References 82
  • Chapter IV - Macromolecules 83
  • References 85
  • References 93
  • References 107
  • References 111
  • Part Two - Enzymes and Biochemical Energetics 129
  • Chapter I - General Principles of Biochemical Energetics 131
  • References 150
  • Chapter II - Enzymes 151
  • References 176
  • Part Three - Chemical Reactions in the Biosphere 177
  • Introduction 179
  • Chapter I - Destructive and Non-Destructive Methods in Modern Biochemistry 181
  • References 182
  • References 184
  • References 185
  • Chapter II - Priming Reactions 186
  • References 197
  • References 199
  • References 207
  • References 209
  • References 223
  • Chapter III - Biosyntheses 229
  • Part Four - Topobiochemistry and Cellular Regulation 271
  • Chapter I - Cellular Topochemistry 273
  • Conclusions 280
  • References 280
  • Chapter II - Cellular Regulation 282
  • References 286
  • Part Five - Biochemical Diversity 287
  • Chapter I - Some Aspects of Biochemical Diversity 289
  • References 303
  • Chapter II - The Inheritance of Biochemical Characteristics 304
  • References 316
  • Chapter III - Biochemistry and Taxonomy 317
  • References 332
  • Chapter IV - Biochemical Evolution 333
  • References 335
  • References 345
  • Part Six - The Metabolism of the Biosphere 347
  • Introduction 349
  • Chapter I - Entry into the Biosphere 351
  • References 365
  • Chapter II - Departure from the Biosphere 366
  • References 370
  • Chapter III - The Cycles 371
  • References 380
  • Index 381
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