Encyclopedia of Reproductive Technologies

By Annette Burfoot | Go to book overview
increase in incidence over the normal incidence for the population in question.
Conclusion
In summary, research has demonstrated that ovulation induction is associated with serious, sometimes life-threatening, events. Severe ovarian hyperstimulation syndrome still occurs in about 1 in 50 to 1 in 100 women in spite of careful monitoring. Multiple pregnancy frequently complicates ovulation-induced and assisted-conception pregnancies. Perinatal mortality is excessive. Recent data suggest that ovulation induction may also be a risk factor for extrauterine pregnancy, neural tube defects, defects in reproductive organogenesis, malignant neoplasms, and hydatidiform mole.
FOR FURTHER READING
McEvoy, G. K., ed. 1990. American Hospital Formulary Services. Bethesda, Md.: American Society of Hospital Pharmacists.
Ron, E., B. Lunenfeld, J. Menczer, et al. 1987. "Cancer Incidence in a Cohort of Infertile Women." American Journal of Epidemiology 125( 5): 780-790.
Stephenson, P. 1993. "Ovulation Induction During Treatment for Infertility: An Assessment of the Risks." In P. Stephenson and M. G. Wagner, eds., "Tough Choices: In Vitro Fertilization and the Reproductive Technologies". Philadelphia: Temple University Press.
U.S. Pharmacopeial Convention. 1990. Drug Information for the Health Care Professional. Rockville, Md.: USPC.
Whittemore, A. S., et al. 1992. "Characteristics Relating to Ovarian Cancer Risk: Collaborative Analysis of 12 U.S. Case-control Studies." American Journal of Epidemiology 15: 1184-1203.

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