ferent parts of the world to a defined interdisciplinary field pursued by established behavioral scientists, neuroscientists, and immunologists. The field can now be characterized as sailing between the Scylla of pseudoscience (e.g., an advertisement for "The Immune Power Diet") and the Charybdis of "molecularization" that ignores thoughts, feelings, and behaviors, as well as the clinical medical psychology from which the field arose.
As the field dealing with the complex bidirectional CNS-immune system interactions, psychoneuroimmunology can provide specific testable hypotheses with regard to HIV diseases or AIDS-spectrum disorders. At this point in psychoneuroimmunologic research on AIDS, there are many questions and virtually no answers. We believe, however, that by posing some of these questions in the context of previous work in psychoneuroimmunology and our own preliminary findings, other researchers may be stimulated to approach this research frontier. Further, we believe that HIV/AIDS as a multifactoral disease offers a unique opportunity to explore the relationships among psychological, immunologic, neurologic, and health-outcome variables.
The psychoimmunologic AIDS research reported here was supported by NIMH Grant #MH 39344 ( Lydia Temoshok, Principal Investigator). We wish to acknowledge the members of the University of California Biopsychosocial AIDS Project who have been involved in this research formally since 1983.
Please send reprint requests and all correspondence to: George F. Solomon, M.D., Veterans Administration Medical Center, 116A-10, 16111 Plummer Street, Sepulveda, CA 91343.
Adams F. Quesada J. R. & Gutterman J. U. ( 1984). "Neuropsychiatric manifestations of human leukocyte interferon therapy in patients with cancer". Journal of the American Medical Association, 252, 938-941.
Ader R. (Ed.). ( 1981). Psychoneuroimmunology. New York: Academic Press.
Bartrop R. W. Luckhurst, L.Lazarus L. G.Kiloh R., & Penny R. ( 1977). "Depressed lymphocyte function after bereavement". Lancet, 1, 343-836.
Blair P. B. ( 1981). "Immunologic consequences of early exposure of experimental rodents to diethylstibestrol and steroid hormones". In A. L. Herbst & H. A. Berm (Eds.), Developmental effects of diethylstilbestrol in pregnancy (pp. 167-178). New York: Thieme-Stratton.
Borysenko M. ( 1984, June). Immunological alterations underlying tumor growth promoting effects of stress in mice. Paper presented at the Joint Symposium of the European Working Group for Psychosomatic Cancer Research and the R. E. Kavetsky Institute of Oncolony Problems. Kiev, U.S.S.R.